Anaerobic growth is very slow (One glucose: 2 ATPs)
Aerobic respiration allows faster growth (One glucose: 38
ATPs)
Aerobic Respiration
Krebs cycle + Electron transport chain + Chemiosmosis
+ Oxidative Phosphorylation
1) Krebs Cycle: Pyruvate converted to acetyl-CoA, oxidized
in cycle
-In prokaryote cytoplasm
-Generates CO2, some ATP
-Most important: Generates NADH, FADH2
reducing potential
2) Electron Transport:
-At cell membrane
-NADH, FADH2 pass electrons via carriers
to O2
-H+ pumping creates gradient
3) Chemiosmosis: Proton gradient provides energy for ATP synthesis by oxidative phosphorylation
Review Tables 5.2 and 5.3, p. 125
Alternative energy sources: Lipids, Proteins
1) Lipids hydrolyzed to acetyl-CoA, fed into Krebs cycle
2) Proteins hydrolyzed to amino acids, deaminated, fed into
glycolysis or Krebs cycle
Amphibolic pathways: Catabolic pathways provide intermediates
for anabolic synthesis pathways and vice versa